Saturday, February 27, 2010

Objective Surgical Skill Metrics

My research focuses on methods for automated, quantitative analysis of surgical skill. Given the wealth of tool-path data coming from simulation platforms and surgical robots, my particular interest is in deriving dynamic metrics that could make full use of this data. Cumulative metrics like time, path length, economy of motion, etc., only give general (though important) feedback about a procedure as a whole: a summary approach. However, dynamic metrics should reveal key information about skill or ineptitude for times within a procedure, and so be able to index when during a procedure such phenomena occurred. This could facilitate proximate feedback that promises to accelerate learning curves for surgical skill.

Literature reporting and exploring dynamic metrics:
  • None :) I have yet to find a publication that really pursued this. Some did employ techniques that could be used in a dynamic analysis, but only cumulative information was analyzed. These appear below

Surgical/Clinical Literature relevant for deriving dynamic metrics
  • Gallagher AG, Ritter EM, Champion H, et al. Virtual reality simulation for the operating room: proficiency-based training as a paradigm shift in surgical skills training. Ann Surg 241:364-72, 2005. [Link] Citation Count: 18o. Introduces the notion of attentional resources: attentional demand is significantly strained by lack of visuo-spatial and psychomotor skills. Also suggests proficiency-based training as an important direction for the field.
  • Watterson JD, Beiko DT, Kuan JK, et al. A randomized prospective blinded study validating acquisition of ureteroscopy skills using a computer based virtual reality endourological simulator. J Urol 168:1928-32, 2002. [Link] Citations: 710. Introduced a 1-minute window for error evaluation. Though it's purpose was simply to make error analysis easy and less artifact-prone, the 1-minute window idea could have been easily extended into a video indexing and proximate feedback scheme. However, performance was scored via expert video evaluation, which does not lend itself to objectivity, automation, or scale well.
  • Satava, RM, Cuschieri, A, Hamdorf, J. Metrics for objective assessment. Surg Endo 17:220-226, 2003. [Link] Citations: 67. Attempted a comprehensive survey of metrics, metrics categories, skills, etc. as well as the technologies that do or don't provide them. The document was lacking in detail or development of the notions, but I think the idea of comprehensive analysis was important. Besides, how could any lit review about surgical metrics not have a Satava ref?
  • The FLS Program (Fundamentals of Laparoscopic Skills) is also important to mention in the skill evaluation context. It incorporates proficiency-based training and a cost effective training approach. Most importantly it's been validated in multiple ways. However, no mention or effort is made for dynamic metrics or proximate feedback. However, FLS tasks present a nice, validated platform for studying basic skill acquisition and developing dynamic surgical metrics. The Link given above has a nice list of references following the inception (MISTEL's) of the tasks, their adoption, and validation. Citation counts average at about 70, with key publications being at 255 (the original, Derossis, American Journal of Surgery 1998), 181 (Fried, Annals of Surgery,2004), 102 (Coll of Surg, 2005).
  • Judkins TN, Oleynikov D, Stergiou N. Objective evaluation of expert and novice performance during robotic surgical training tasks. Surg Endosc (2008). [Link]. A similar publication appears in the Journal of Robotic Surgery with the same authors and a similar title. This work focuses on robotic surgery and incorporates some more sophisticated metrics like curvature and relative phase analysis (a technique from the dynamical systems paradigm of motor learning). But, results were only presented as cumulative info.

Engineering/Computer Science literature
    • J. Rosen, B. Hannaford, C. Richards, and M. Sinanan, “Markov modeling of minimally invasive surgery based on tool/tissue interaction and force/torque signatures for evaluating surgical skills,” IEEE Trans. Biomed. Eng., vol. 48, no. 5, pp. 579–591, May 2001. [Link] Citations: 95. This is the BioRbotics Lab classic which used tool-path data from lapr. procedures done on live pigs and treated it as a signal processing/machine learning problem. Markov models were used and Hidden Markov Models were later evaluated as well. There are several incremental improvements using this approach (or variations of it) that can easily be google'd.

    My suspicion is that someone, somewhere has to have done some work in this area, I just haven't found the publications yet. Any suggestions would be most welcome.

    Friday, February 5, 2010

    An Instrumented Surgical Tool for Ischemia Detection --- Seminal Papers

    Ischemia Detection:

    1. O. Casas, R. Bragos, P.J. Rui, J. Rosell, M. Tresanchez ad M. Warren, A. Rodriguez-Sinovas, A. Carreno, and J. Cinca. In vivo and in situ ischemic tissue characterization using electrical impedance spectroscopy. Annals New York Academy of Sciences, 873:51–58, 1999.
    2. Stevan Kun and Robert A. Peura. Tissue ischemia detection using impedance spectroscopy. In IEEE Engineering in Medicine and Biology Society, volume 2, pages 868–869, 1994.
    3. Shai Friedland, David A. Benaron, Sheila Coogan, Daniel Y. Sze, and Roy Soetikno. Diagnosis of chronic mesenteric ischemia by visible light spectroscopy during endoscopy. Gastrointestinal Endoscopy, 65(2):294–300, 2007.

    Tools with Integrated Sensing:

    1. Gregory S. Fischer, Takintope Akinbiyi, Sunipa Saha, Jason Zand, Mark Talamini, Michael
      Marohn, and Russell Taylor. Ischemia and Force Sensing Surgical Instruments for Augmenting Available Surgeon Information. In International Conference on Biomedical Robotics and Biomechatronics, February 2006.
    2. J.D. Brown, J. Rosen, M. Moreyra, M. Sinanan, and B. Hannaford. Computer-controlled motorized endoscopic grasper for in vivo measurements of soft tissue biomechanical characteristics. Studies in Health Technology and Informatics - Medicine Meets Virtual Reality, 85:71–73, January 2002.

    Wednesday, February 3, 2010

    Small Diameter MIS Tools - Seminal Papers

    Brain Tissue Properties:

    MS Estes and JH McElhaney. Response of Brain Tissue to Compressive Loading. ASME Paper No. 70-BHF-13, 1970.

    G. Franceschini, D. Bigoni, P. Regitnig, and GA Holzapfel. Brain tissue deforms similarly to filled elastomers and follows consolidation theory. Journal of the Mechanics and Physics of Solids, 54(12):2592-2620, 2006.


    Force Scaling:

    A. Menciassi, A. Eisinberg, I. Izzo, and P. Dario. From "Macro" to "Micro" Manipulation: Models and Experiments. IEEE/ASME Transactions on Mechatronics, 9(2):311-320, Jun 2004.

    AM Petrina. Micromanipulation in Robotics. Automatic Documentation and Mathematical Linguistics, 42(1):66-70, Feb 2008.


    Micro Assembly

    R. Sahai, J. Lee, and RS Fearing. Semi-Automated Micro Assembly for Rapid Prototyping of a One DOF Surgical Wrist. IEEE/RSJ International Conference on Intelligent Robots and Systems, 2, Oct 2003.

    Monday, February 1, 2010

    Error in Critical Care (Vankipuram) - Seminal Papers

    Posted below are links to some interesting work in the domain.

    Weingart SN, Wilson RM, Gibberd RW, Harrison B. Epidemiology of medical error. BMJ. 2000;320(7237):774–7

    I found that Weingart et al. in this work provide a good introduction to the topic of medical error, highlighting the impact errors can have on patient outcome. The paper also discusses the types of errors that have occurred in the literature, in addition to an analysis of impact of clinician experience on error occurrence.

    The rest of the papers discuss methods by which workflow is monitored. One of my research aims is to develop a method that combines qualitative and quantitative techniques to enhance workflow monitoring.

    Malhotra S, Jordan D, Shortliffe E, Patel VL. Workflow modeling in critical care: Piecing together your own puzzle. Journal of Biomedical Informatics. 2007;40(2):81-92.

    Laxmisan A, Hakimzada F, Sayan OR, Green RA, Zhang J, Patel VL. The multitasking clinician: Decision-making and cognitive demand during and after team handoffs in emergency care. International Journal of Medical Informatics. 2007;76(11-12):801-11.

    Malhotra et al. and Laxmisan et al. have utilized qualitative methods (observations, interviews, chart analysis) for analyzing workflow in critical care units. Some of the advantages of qualitative techniques (high quality of information gathering) are evident in these works.

    Fry EA, Lenert LA. MASCAL: RFID tracking of patients, staff and equipment to enhance hospital response to mass casualty events. AMIA Annual Symposium Proceedings.
    2005:261-5

    Chen C, Liu C, Li Y, Chao C, Liu C, Chen C, et al. Pervasive Observation Medicine: The Application of RFID to Improve Patient Safety in Observation Unit of Hospital Emergency Department. IOS Press; 2005.

    Fry and Lenert, and Chen et al. present some exciting research of incorporating RFID in the healthcare setting to impact workflow.

    Looking forward to your feedback on these papers!

    Sunday, January 24, 2010

    Reference for "Robotic, Multi-Articulated Endoscopic Surgical Tools for Natural Orifice Translumenal Endoscopic Surgery"

    Please see below some of the references I have found to be helpful/influential:

    Introduction to NOTES procedures:

    Kalloo, A.N., Singh, V.K., Jagannath, S.B., Niiyama, H., Hill, S.L., Vaughn, C.A., Magee, C.A., and Kantsevoy, S.V., 2004. Flexible transgastric peritoneoscopy: a novel approach to diagnostic and therapeutic interventions in the peritoneal cavity. Gastrointestinal Endoscopy, 60(1), pp. 114-117.

    Rattner, D. and Kalloo, A., 2006. ASGE/SAGES Working Group on Natural Orifice Translumenal Endoscopic Surgery. Surgical Endoscopy, 20, pp. 329-333.

    Bergman, S. and Melvin, W.S., 2008. Natural orifice translumenal endoscopic surgery. Surgical Clinics of North America, 88, pp. 1131-1148.

    On the development of devices for NOTES:

    Bardaro, S.J. and Swanstrom L., 2006. Development of advanced endoscopes for Natural Orifice Transluminal Endoscopic Surgery (NOTES). Minimally Invasive Surgery, 15(6), pp. 378-383.

    On actuation methods:

    Granosik, G. and Borenstein, J., 2005. Pneumatic actuators for serpentine robot. 8th International Conference on Walking and Climbing Robots, pp. 719-726, London.


    Bonus, update on current NOTES status:

    Gostout, C.J., 2009. Update on the use of NOTES procedures. Advances in Endoscopy, 5(6), pp. 401-405.


    I'm looking forward to meeting everyone and getting some great feedback.

    Seminal references on "Haptic Endoscopic Instrument for Manipulation of Large Organs"

    Hi All,

    My seminal references are:

    On large internal organs manipulation:

    R. Ohshima, T. Takayama, T. Omata, T. Ohya, K. Kojima, K. Takase, and N. Tanaka, "Assemblable three fingered five-DOF hand for laparoscopic surgery," in Proceedings - IEEE International Conference on Robotics and Automation, Pasadena, CA, 2008, pp. 3896-3901.

    On instrumentation and haptic interfaces:

    J. Rosen, B. Hannaford, M. P. MacFarlane, and M. N. Sinanan, "Force controlled and teleoperated endoscopic grasper for minimally invasive surgery--experimental performance evaluation," IEEE Trans Biomed Eng, vol. 46, pp. 1212-21, Oct 1999.

    M. Tavakoli, R. V. Patel, and M. Moallem, "Haptic interaction in robot-assisted endoscopic surgery: a sensorized end-effector," The international journal of medical robotics + computer assisted surgery : MRCAS, vol. 1, pp. 53-63, 2005.

    On Soft tissue grasping:

    E. A. M. Heijnsdijk, H. DeVisser, J. Dankelman, and D. J. Gouma, "Slip and damage properties of jaws of laparoscopic graspers," Surgical Endoscopy and Other Interventional Techniques, vol. 18, pp. 974-979, 2004.

    On large deformation modeling of soft tissue:

    P. J. Davies, F. J. Carter, and A. Cuschieri, "Mathematical modelling for keyhole surgery simulations: A biomechanical model for spleen tissue," IMA Journal of Applied Mathematics (Institute of Mathematics and Its Applications), vol. 67, pp. 41-67, 2002.

    I would gratefully appreciate any suggestion about my topic.

    Saturday, January 23, 2010

    First Discussion Point: Seminal Papers

    Dear Participants,

    a key element of conducting research lies in identifying seminal publication in your areas. It is how we know what the state of the art is and how we can improve it. Your first task and request is to identify 5 seminal papers in your area and post their reference it on the blog...

    I look forward to seeing them!

    Kanav

    Topics for All the Participants

    Devin Berg: Robotic, Multi-Articulated Endoscopic Surgical Tools for Natural Orifice Translumenal Endoscopic Surgery

    Diana Friedman: Small Diameter Tools for MIS

    Yu Ge: Levels-of-Detail Based Multi-resolution Modeling and Rendering for Haptic-enabled Dental Training System

    H Hawkeye King: interoperable telesurgical robotics.

    Alireza Mirbagheri: Design, Analysis and Experimental Study of a Haptic Endoscopic
    Instrument for Manipulation of Large Organs

    Phil Roan: An Instrumented Surgical Tool for Reliable Ischemia Detection

    Tim Kowalewski: A Dynamical Systems-Theoretic Approach To Evaluating Surgical Skill

    Mithra Vankipuram: Error in Critical Care: A Framework for Error Comprehension and Management

    Silvio Rizzi: Volumetric haptic rendering for medical education

    Please correct if you think it needs editing...

    Kanav

    Friday, January 22, 2010

    Topics?

    Hi All,
    Can we share what our dissertation topics are for the consortium? I'd like to hear more about what people are working on. My focus is quantitative analysis of surgical skill using tool path data collected from a variety of sources. Anyone else working with skill evaluation?

    Welcome to the Medical Simulation and Robotics Doctoral Consortium Blog

    A warm welcome to the blog accompanying the NSF sponsored Doctoral Consortium on Medical Simulation and Robotics to be held on March 11th 2010 in Chicago Illinois. The purpose of this blog is to encourage a continuing dialogue between the doctoral candidates and experts on various topics of interest. This is a public blog meant for public discussions. The link to the website of the workshop is at www.medicalsimulationdc.com Visit it for frequent updates!

    We will begin the blog with a simple exercise for all the students. Simply register with the blogspot website and start blogging. Ill put up a topic of discussion this weekend

    Kanav